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Quidel Polyclonal Antiserum to Human C1 Inhibitor (C1 Esterase)
品牌:Quidel
货号:A300
规格:2.0 mL
货期:现货

商品详情 参考文献 相关资料

产品介绍

品名

Quidel Polyclonal Antiserum to Human C1 Inhibitor (C1 Esterase)

货号

 A300

规格

2.0 mL 

 形式

Whole Antiserum 

防腐剂

 ≤ 0.1% Sodium Azide

物种交叉反应

Baboon, Dog, Rabbit

储存

2°C to 8°C  (≤ 30 days)

For long-term storage (> 30 days), aliquot and store at ≤ –20°C. Avoid repeated freeze-thaw.

使用说明

For Research Use Only. Not for use in diagnostic procedures

产品描述

Highly purified human C1-inhibitor was isolated from normal serum and used to immunize goats. The C1-inhibitor polyclonal antisera was tested against normal human plasma by double immunodiffusion, one-dimensional immunoelectrophoresis, quantitative radial immunodiffusion, and quantitative rocket immunoelectrophoresis. The antiserum was determined to be monospecific for C1-inhibitor at varying concentrations.

Quidel Polyclonal Antiserum to Human C1 Inhibitor (C1 Esterase)

背景

C1-inhibitor is a multispecific protease inhibitor present in human plasma and serum. Normal human serum shows a concentration of approximately 200 µg/mL. C1-inhibitor is a glycoprotein with an approximate molecular weight of 110 kD. This protein contains many glycosylation sites, so the molecular weight varies depending on the quantity of sites that are glycosylated

应用

Applications of the C1-inhibitor polyclonal antisera have been evaluated by various research facilities, and include Western Blot 1 and Immunoblot. 2

参考文献

Schwab, J. et al. “Borrelia valaisiana Resist Complement-Mediated Killing Independently of the Recruitment of Immune Regulators and Inactivation of Complement Components.” PLoS ONE 8(1): e53659. 

Yasojima, K., et al. “Complement Components, but Not Complement Inhibitors, are Upregulated in Atherosclerotic Plaques.” Arteriosclerosis, Thrombosis, and Vascular Biology (2001): 1214-1219


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