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DiscoverX Flt1, active 14-923-K

品牌：Eurofins DiscoverX

货号：14-923-K

规格：14-923-K

货期：DiscoverX

应用：

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品牌：DiscoverX 品名：Flt1, active 货号：14-923-K 规格：Bulk

商品详情参考文献相关资料

品牌：DiscoverX
品名：Flt1, active
货号：14-923-K
规格：Bulk

简要说明：

Flt1, active

N-terminal GST-tagged recombinant, human Flt1 amino acids 783-end. This protein encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

产品介绍：

Target

Flt1

Expression System

Expressed by baculovirus in Sf21 insect cells

Application

Kinase Assay

Molecular Weight

89 kDa

Accession Number

AF063657

Species

Human

Tag

GST

Purification Method

Glutathione Sepharose™ affinity chromatography

Content

Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.

Storage

6 months at -70°C

Bulk Sizes

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