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DiscoverX CLK1, active 14-920M
品牌:Eurofins DiscoverX
货号:14-920M
规格:14-920M
货期:DiscoverX

品牌:DiscoverX 品名:CLK1, active 货号:14-920M 规格:250 µg

商品详情 参考文献 相关资料
品牌:DiscoverX
品名:CLK1, active
货号:14-920M      
规格:250 µg

简要说明:

CLK1, active

N-terminal 6His-tagged recombinant, human CLK1 amino acids 130-end.CLK1 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.


产品介绍:

Target
CLK1
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
45 kDa
Accession Number
NM_004071
Species
Human
Tag
6His
Purification Method
Immobilised metal affinity chromatography
Content
Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Storage
6 months at -70°C
Bulk Sizes
Inquire

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