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DiscoverX PI3 Kinase (p110alpha(E542K) p85alpha) 14-782M
品牌:Eurofins DiscoverX
货号:14-782M
规格:14-782M
货期:DiscoverX

品牌:DiscoverX 品名:PI3 Kinase (p110α(E542K)/p85α) 货号:14-782M 规格:250 µg

商品详情 参考文献 相关资料

品牌:DiscoverX
品名:PI3 Kinase (p110α(E542K)/p85α)
货号:14-782M  
规格:250 µg

简要说明:

PI3 Kinase (p110α(E542K)/p85α)

Complex of N-terminal 6His-tagged recombinant, human full length p110α containing the mutation E542K and untagged, recombinant, full length human p85α. The E542K substitution is a somatic mutation in p110α that has been associated with tumours of the colon and brain. Combined in vitro and in vivo studies have shown that this mutation confers higher lipid kinase activity than wild type, and is able to induce oncogenic transformation.


产品介绍:

Target
PI3Kα/p85α
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
125.3 kDa (p110α E542K), 83.7 kDa (p85α)
Accession Number
NM_006218.2
Species
Human
Tag
6His
Purification Method
Ni2+/NTA-agarose
Storage
6 months at -70°C
Bulk Sizes
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