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DiscoverX Tie2 (R849W), active 14-763-K
品牌:Eurofins DiscoverX
货号:14-763-K
规格:14-763-K
货期:DiscoverX

品牌:DiscoverX 品名:Tie2 (R849W), active 货号:14-763-K 规格:Bulk

商品详情 参考文献 相关资料

品牌:DiscoverX
品名:Tie2 (R849W), active
货号:14-763-K  
规格:Bulk  

简要说明:

Tie2 (R849W), active

N-terminal 6His-tagged recombinant, human Tie2 amino acids 771-end containing the R849W substitution. The R849W mutation has been reported in dominantly inherited venous malformations. Expression studies in insect and mammalian cells demonstrates that Tie2 R849W has constitutively elevated tyrosine kinase activity compared with wild type. (Morris P.N., et al., Biochem.Biophys.Res.Commun.(2006);346:335-338 and Vikkula M, et al., Cell(1996);87:1181-1190).


产品介绍:

Target
Tie2
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
42 kDa
Species
Human
Tag
6His
Purification Method
Ni2+/NTA-agarose
Content
Protein in 50mM Tris/HCl pH8.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij 35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Storage
6 months at -70°C
Bulk Sizes
Inquire


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