Anti-FANCG (Phospho-Ser383) Antibody |产品详情|进口试剂采购网

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Anti-FANCG (Phospho-Ser383) Antibody

品牌：Antibodies

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规格：50µl

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Anti-FANCG (Phospho-Ser383) Antibody

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Name:	Anti-FANCG (Phospho-Ser383) Antibody See all FANCG primary antibodies
Description:	Rabbit polyclonal antibody to FANCG (Phospho-Ser383)
Specificity:	The antibody detects endogenous levels of FANCG only when phosphorylated at serine 383.
Applications:	WB
Dilutions:	Western blotting: 1:500~1:3000
Reactivity:	Human
Immunogen:	Peptide sequence around phosphorylation site of serine 383 (R-F-S(p)-P-P) derived from Human FANCG.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20˚C

Function:	DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
Tissue Specificity:	Highly expressed in testis and thymus. Found in lymphoblasts.
Involvement in Disease:	Fanconi anemia complementation group G: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
Cellular Location:	Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
Database Links:	Entrez Gene: 2189 Human Omim: 602956 Human SwissProt: O15287 Human Unigene: 591084 Human
Synonyms:	DNA repair protein XRCC9 Antibody FAG Antibody FANCG Antibody FANCG_HUMAN Antibody Fanconi anaemia complementation group G Antibody Fanconi anemia group G protein Antibody Protein FACG Antibody X ray repair, complementing defective, in Chinese hamster cells 9 Antibody X-ray repair, complementing defective, in Chinese hamster, 9 Antibody XRCC9 Antibody
Information:	Target information shown above is from the UniProt Consortium.