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DiscoverX IKKε, active 14-926M
品牌:Eurofins DiscoverX
货号:14-926M
规格:14-926M
货期:DiscoverX

品牌:DiscoverX 品名:IKKε, active 货号:14-926M 规格:250 µg

商品详情 参考文献 相关资料

品牌:DiscoverX
品名:IKKε, active
货号:14-926M      
规格:250 µg

简要说明:

IKKε, active

N-terminal FLAG, GST-tagged recombinant, human IKKε full length. IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death.

产品介绍:

Target
IKKe
Expression System
Expressed by baculovirus in Sf21 insect cells
Application
Kinase Assay
Molecular Weight
109 kDa
Accession Number
NM_001193321.1
Species
Human
Tag
GST, FLAG
Purification Method
Immunoaffinity chromatography
Content
Protein in 50mM Tris/HCl pH7.5, 150mM NaCl, 10mM β-glycerophosphate, 1mM sodium orthovanadate, 1mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
Storage
6 months at -70°C
Bulk Sizes
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