DiscoverX FGFR1 (V561M), active 14-734M 14-734M|产品详情|进口试剂采购网

您好，欢迎来到拜力生物网站！请登录注册

我的订单 | 联系我们 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA试剂盒、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口试剂、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于我们

所在位置：首页 > 产品中心 > discoverx

订购信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

DiscoverX FGFR1 (V561M), active 14-734M

品牌：Eurofins DiscoverX

货号：14-734M

规格：14-734M

货期：DiscoverX

应用：

咨询客服

立即购买加入购物车

品牌：DiscoverX 品名：FGFR1 (V561M), active 货号：14-734M 规格：250 µg

商品详情参考文献相关资料

品牌：DiscoverX
品名：FGFR1 (V561M), active
货号：14-734M
规格：250 µg

简要说明：

FGFR1 (V561M), active

N-terminal GST-tagged recombinant, human FGFR1 amino acids 456 - 765 containing the V561 mutation. The coordinates for recombinant human FGFR1 were described in Homann et al. (2001). Blencke et al. (2004) suggested mutations to a conserved threonine residue at the ATP binding site would result in inhibitor resistance. The amino acid valine 561 was mutated to a methionine in FGFR1 which corresponded to previously reported mutations found in Abl (T315) and EGFR (T766) which had been shown to confer resistance to selective inhibitors. Assay data for FGFR1 V561M had shown that this mutation had conferred resistance to PP58 (pyrido [2,3-d] pyrimidine tyrosine kinase inhibitor) compared to that of the wild type.

产品介绍：

Target

FGFR1

Expression System

Expressed by baculovirus in Sf21 insect cells

Application

Kinase Assay

Molecular Weight

62.3 kDa

Species

Human

Tag

GST

Purification Method

Glutathione agarose affinity chromatography

Content

Protein in 50mM Tris/HCl pH 7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij 35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.

Storage

6 months at -70°C

Bulk Sizes

Inquire

热销产品