Catalogue number
PRO-2211
Synonyms
Beta-sarcoglycan, Beta-SG, 43 kDa dystrophin-associated
glycoprotein, 43DAG, A3b, LGMD2E, Sarcoglycan, Beta (43kDa
Dystrophin-Associated Glycoprotein), Limb Girdle Muscular Dystrophy 2E
(Non-Linked Families), SGC.
Introduction
Sarcoglycan
Beta, also known as SGCB, is a part of the sarcoglycan family. SGCB belongs to the
sarcoglycan complex which is a subcomplex of the dystrophin-glycoprotein
complex that connects between the F-actin cytoskeleton and the extracellular
matrix.
Description
SGCB Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 255 amino acids (87-318 a.a) and
having a molecular mass of 27.8kDa.
SGCB is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
SGCB protein solution (0.5mg/ml) containing 20mM Tris-HCl
buffer(pH8.0) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4
weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier
protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH
SSGLVPRGSH MGSWAVIRIG
PNGCDSMEFH ESGLLRFKQV SDMGVIHPLY KSTVGGRRNE NLVITGNNQP IVFQQGTTKL SVENNKTSIT
SDIGMQFFDP RTQNILFSTD YETHEFHLPS GVKSLNVQKA STERITSNAT SDLNIKVDGR AIVRGNEGVF
IMGKTIEFHM GGNMELKAEN SIILNGSVMV STTRLPSSSS GDQLGSGDWV RYKLCMCADG TLFKVQVTSQ
NMGCQISDNP CGNTH.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
