Catalogue number
PRO-1677
Synonyms
Tumor suppressor candidate 2, C3orf11, FUS1, PAP, PDAP2, TUSC2,
Fusion 1 protein, Fus-1 protein, PDGFA-associated protein 2, LGCC.
Introduction
Tumor Suppressor Candidate 2, also known as TUSC2, is a part of the TUSC2 family. TUSC2 protein functions as a tumor suppressor, inhibiting colony formation, causing G1 arrest and eventually inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
Description
TUSC2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 133 amino acids (1-110) and having a molecular mass of 14.5 kDa.
TUSC2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The TUSC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMGASGSK ARGLWPFASA AGGGGSEAAG AEQALVRPRG RAVPPFVFTR RGSMFYDEDG DLAHEFYEET IVTKNGQKRA KLRRVHKNLI PQGIVKLDHP RIHVDFPVIL YEV.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
