IFN-Induced Protein With Tetratricopeptide Repeats 3, IFN-Induced Protein With Tetratricopeptide Repeats 4, IFIT4, Retinoic Acid-Induced Gene G Protein, IFN-Induced 60 KDa Protein, IFI-60K, CIG-49, IFIT-3, IFIT-4, ISG-60, CIG49, IFI60, ISG60, RIG-G, P60, GARG-49, IRG2, IFN-induced protein with tetratricopeptide repeats 3.
IFN-Induced Protein With Tetratricopeptide Repeats 3, also known as IFIT3 is a member of the IFIT family. IFN-induced antiviral protein which performs as an inhibitor of cellular and viral processes, cell migration, proliferation, signaling, as well as viral replication. Furthermore, IFIT3 is significantly induced upon RNA virus infection. Ectopic expression or alternatively knockdown of IFIT3 might, respectively, enhance or impair IRF3-mediated gene expression.
IFIT3 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 513 amino acids (1-490 a.a) and
having a molecular mass of 58.4kDa.
IFIT3 is fused to a 23
amino acid His-tag at N-terminus & purified by proprietary chromatographic
techniques.
E.coli.
Sterile Filtered colorless solution.
IFIT3 protein solution (1mg/ml) containing Phosphate
buffered saline (pH7.4), 20% glycerol and 1mM DTT.
Greater than 80% as determined by SDS-PAGE.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
