Catalogue number
PRO-2201
Synonyms
Macrophage Scavenger Receptor 1, SCARA1, Macrophage Acetylated LDL Receptor I And II, Scavenger Receptor Class A Member 1, SRA, Macrophage Scavenger Receptor Types I And II, Macrophage Scavenger Receptor Type III, Scavenger Receptor Class A, Member 1 CD204 Antigen, CD204, PhSR1, PhSR2, SR-A.
Introduction
Macrophage Scavenger Receptor 1, also known as MSR1 is a member of the
class A macrophage scavenger receptors, which comprises three different types 1,
2 and 3 generated by alternative splicing. Furthermore, these receptors or
isoforms are macrophage-specific trimeric integral membrane glycoproteins and
have been implicated in many macrophage-associated physiological as well as
pathological processes which include atherosclerosis, Alzheimer's disease, and
host defense.
Description
MSR1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 398 amino acids (77-451 a.a) and having a molecular mass of 43.7kDa.
MSR1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
MSR1 protein solution (0.5mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSKWETKNC SVSSTNANDI TQSLTGKGND SEEEMRFQEV FMEHMSNMEK RIQHILDMEA NLMDTEHFQN FSMTTDQRFN DILLQLSTLF SSVQGHGNAI DEISKSLISL NTTLLDLQLN IENLNGKIQE NTFKQQEEIS KLEERVYNVS AEIMAMKEEQ VHLEQEIKGE VKVLNNITND LRLKDWEHSQ TLRNITLIQG PPGPPGEKGD RGPTGESGPR GFPGPIGPPG LKGDRGAIGF PGSRGLPGYA GRPGNSGPKG QKGEKGSGNT LTPFTKVRLV GGSGPHEGRV EILHSGQWGT ICDDRWEVRV GQVVCRSLGY PGVQAVHKAA HFGQGTGPIW LNEVFCFGRE SSIEECKIRQ WGTRACSHSE DAGVTCTL
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
