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APC - anti mouse CD115 - Clone CSF-1R
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APC - anti mouse CD115 - Clone CSF-1R
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APC - anti mouse CD115 - Clone CSF-1R
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APC - anti Mouse CD115 - CSF-1R

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90,00 € tax excl.

275,00 € tax excl.

Product Description

  • CSF-1R
  • Rat IgG2a
  • Flow Cytometry
  • APC
  • 0.2 mg/ml
  • Mouse CD115 Recombinant Protein
  • Mouse
  • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
  • RUO
  • Liquid
  • Store in the dark at 2-8 °C
Mouse APC Vial View larger
CD115 is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
  • CSF-1R, M-CSFR, c-fms
  • 145 kD
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