Alpha-2-Plasmin Inhibitor PRODUCT INQUIRY a2–plasmin inhibitor and fibrinolysis The primary physiological inhibitor of plasmin is a2–plasmin inhibitor. The binding of a2 –plasmin inhibitor to plasmin(ogen) plays a critical role in fibrinolysis. The binding of circulating free plasmin(ogen) by a2 –plasmin inhibitor prevents both zymogen and enzyme from binding to fibrin and ultimately initiating fibrinolysis. a2–Plasmin inhibitor already crosslinked to fibrin prevents plasmin catalytic action on local sites of fibrin deposition as well as impeding subsequent activation of plasminogen via plasminogen activator. HA2AP-0230 Alpha-2-Plasmin Inhibitor (human) Pricing: Please Inquire SAMPLE DATA SHEET | SAFETY DATA SHEET Size 100µg Formulation 50 KPO4, 7.5 mM KCl, 75 uM EDTApH 7.4 Molecular Weight Storage -80°C Purity >95% by SDS-PAGE Compound Assay Plasmin inhibition assay Shelf Life (properly stored) 12 months Chemical Formula