TCEB2 Antibody is a Rabbit Polyclonal antibody against TCEB2. This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.

Target	TCEB2
Reactivity	Human, Mouse
Origin	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IP
Recommended dilutions	WB: 1/500 - 1/2000, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human TCEB2.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 13 kDa/17 kDa Observed MW: 15 kDa
Swiss Prot	Q15370
GeneID	6923
Gene Symbol	TCEB2
Concentration	> 1 mg/ml
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.