NGAL (Capture Ab) is a capture antibody for use in WB, LF and ELISA assays. Use abx019242 as a detection antibody. Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.

Target	NGAL
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Tested Applications	ELISA, WB, LF
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant human NAGL.
Purity	> 95% by HPLC & SDS-PAGE.
Purification	Protein A or G purified.
Form	Liquid
Isotype	IgG1
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P80188 B2ZDQ1
GeneID	3934
Gene Symbol	LCN2
OMIM	600181
HGNC	6526
Ensembl	ENSG00000148346
Concentration	5.36 mg/ml
Buffer	0.01 M PBS (pH 7.4). Does not contain preservatives.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.