TRKA (also known as NTRK1) is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Target	TRKA
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Tested Applications	FCM
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human TRKA.
Purification	Purified Rabbit Polyclonal Antibody.
Isotype	IgG
Conjugation	Unconjugated
Specificity	This TRKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the Central region of human TRKA.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P04629
Buffer	PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.