Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]). This antibody is supplied as crude ascites.

Target	Beclin 1
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Tested Applications	IHC
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human Beclin 1.
Purification	Mouse Monoclonal Antibody (Mab) supplied as crude ascites.
Isotype	IgG3κ
Conjugation	Unconjugated
Specificity	This Beclin 1 antibody was raised using purified His-tagged recombinant full length human Autophagy BECN1.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	Q14457
NCBI Accession	NP_003757.1
Buffer	PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.