CD26 (also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein) is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.

Target	CD26
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Tested Applications	FCM
Recommended dilutions	FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Tissue / cell preparation (Human): Peripheral Blood Lymphocytes.
Purification	Affinity Chromatography
Form	Liquid
Isotype	IgG2b
Conjugation	CF-Blue
Specificity	CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides.
Storage	Store in the dark at 2-8 °C.
Molecular Weight	110kDa
Swiss Prot	P27487
GeneID	1803
Enzyme Commission Number	EC 3.4.14.5
Buffer	The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide
Availability	Shipped within 3-5 working days.
Note	This product is for research use only.