ATP1A2 Antibody is a Rabbit Polyclonal antibody against ATP1A2. The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.

Target	ATP1A2
Reactivity	Human, Mouse, Rat
Origin	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC, IF/ICC, FCM
Recommended dilutions	WB: 1/500 - 1/1000, IHC: 1/20 - 1/50, IF/ICC: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human ATP1A2.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 112 kDa Observed MW: 100 kDa
Swiss Prot	P50993
GeneID	477
Gene Symbol	ATP1A2
Concentration	> 1 mg/ml
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.