The monoclonal antibody is directed against the CD10- antigen (CALL-antigen), which is expressed on human lymphoblasts. The antibody reacts with early B lymphocytes (stem-cell, pre-B) and with the stem-cell of the lymphocyte lineage and immature thymocytes. Lymphoblasts of a patient with an Acute Lymphocytic Leukaemia of the c-ALL type were found to be positive.

Target	CD10
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Tested Applications	FCM
Recommended dilutions	FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	NALM6 human peripheral blood leukemia pre-B cell line.
Purification	Affinity Chromatography
Form	Liquid
Isotype	IgG1
Conjugation	PerCP
Specificity	CD10 clon HI10a recognizes neutral endopeptidase, a 95 kD type II transmembrane glycoprotein, which is refered as the Common Acute Lymphoblastic Leukemia Antigen (CALLA) expressed on common acute lymphoblastic leukaemia cells which is seen on early B-lymphocytes and with stem cells of the lymphocyte lineage and immature thymocytes. The antigen is a neutral endopeptidase.
Storage	Store in the dark at 2-8 °C.
Molecular Weight	95 kDa
Swiss Prot	P08473
GeneID	4311
Buffer	The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide
Availability	Shipped within 2-3 weeks.
Note	This product is for research use only.