IL-7 is a hematopoietic growth factor that primarily affects early B and T cells.  Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2.  Human and murine IL-7 are cross-species reactive.  Recombinant Human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor

AA Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED₅₀ is ≤0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁶ units/mg.