All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine MIP-2 is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-2α, MIP-2α, Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, GRO2

AA Sequence: AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml.