Product Description

Mouse IL-2, Fc Fusion Protein

Interleukin-2 (IL-2) is a O-glycosylated four alpha-helix bundle cytokine that is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells and is required for T-cell proliferation and other activities crucial to regulation of the immune response. This Fc Fusion Protein is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin. Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.