TNFa is presumably shed from cell membranes by TNFa-FW, cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-α converting enzyme (TACE, ADAM17 endopeptidase) activity.
K.M.Mohler et al., Nature, 370, 218 (1994)
A.J.H.Gearing et al., Nature, 370, 555 (1994)
B.F.Becker et al., Biol. Chem., 383, 1821 (2002)
BIOLEAF热搜 BIOLEAF试剂盒 BIOLEAF ELISA BIOLEAF试剂 BIOLEAF品牌 BIOLEAF抗体 BIOLEAF耗材 BIOLEAF小仪器
sitemap 细胞库查询 危险品图标 本公司网站所展示销售的产品仅供科研！
沪公网安备 31011202007338号