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bongkrekic inhibits permeability transition pore, Mitochondrial membrane potent

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bongkrekic inhibits permeability transition pore, Mitochondrial membrane potent

品牌：AG Scientific

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规格：100 ug

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CAS:11076-19-0Formula:C28H38O7‚·3NH3MW:537.7Appearance:LyophilizedsolidPurity:>98%

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Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT) the inner membrane channel of the mitochondrial permeability transition pore(MPTP). It inhibits mitochondrial permeability transition pore opening. At 50 µM it inhibits dexamethasone- apoptosis in thymocytes, preventing the PARP cleavage and DEVDase (caspase-3 like) activity normally produced by these treatment.

Additional Information

Synonyms	BA
Product #	B-1053
CAS #	11076-19-0
Formula	C₂₈H₃₈O₇‚·3NH₃
MW	537.7
Appearance	Lyophilized solid
Purity	>98%
Solubility	Soluble in DMSO. Dilute with destilled water or buffer, pH 7.0-7.5
Melting Point	50-60°C
Preparation	Reconstitute to 1 mg/ml with distilled water
Storage Temp	-20ºC