Ready-to-use colorimetric substrate for caspase-6/Mch2 and related caspases that recognize the amino acid sequence VEID. Caspase-6 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate VEID-pNA, using a spectrophotometer or multi-well plate reader.

Additional Information

Synonyms	Ac-VEID-pNA, Caspase-6 Substrate, Colorimetric
Product #	C-2249
Chemical Name	Ac-VEID-pNA, Caspase-6 Substrate, Colorimetric
Formula	C28H40N6O11
MW	636.7
Appearance	Liquid
Purity	95% by HPLC
Storage Temp	-20°C
Use	Colorimetric substrate for caspase-6/Mch2 and related caspases that recognize the amino acid sequence VEID

Additional Information

MDL Number	MFCD01318842
ChemACX	X1206342-2
InChI	InChI=1S/C28H40N6O11/c1-6-15(4)24(33-25(40)19(11-12-21(36)37)31-27(42)23(14(2)3)29-16(5)35)28(43)32-20(13-22(38)39)26(41)30-17-7-9-18(10-8-17)34(44)45/h7-10,14-15,19-20,23-24H,6,11-13H2,1-5H3,(H,29,35)(H,30,41)(H,31,42)(H,32,43)(H,33,40)(H,36,37)(H,38,39)
SMILES	CCC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C
Peptide Sequence	AC-VAL-GLU-ILE-ASP-PNA