Inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1, or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines.

Additional Information

Synonyms	D-2,3-Dideoxy-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]
Product #	S-2026
Chemical Name	D-2,3-Dideoxy-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]
Formula	C28H57O9P
MW	568.7
Appearance	White to Off-White Solid
Purity	98%
Solubility	Soluble in DMSO, Methanol or Water.
Storage Temp	+4°C
Therapeutic Area	Oncological Disorders
Use	SH-6 is an inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1, or other kinases downstream of Ras such as MAPK. SH-5 induces apoptosis and kills a variety of cancer cell

Additional Information

MDL Number	MFCD06412428
ChemACX	X1497828-2
InChI	InChI=1S/C28H57O9P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-35-22-24(34-2)23-36-38(32,33)37-26-20-19-25(29)27(30)28(26)31/h24-31H,3-23H2,1-2H3,(H,32,33)/t24-,25-,26-,27+,28+/m1/s1
SMILES	CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1CCC(C(C1O)O)O)OC