Ready-to-use colorimetric substrate for caspases that recognize the amino acid sequence AEVD. Caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleaved from the peptide substrate AEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economical alternative for researchers who perform large volume of caspase assays.

Additional Information

Synonyms	Ac-AEVD-pNA, Caspase-10 Substrate, Colorimetric
Product #	C-2230
Chemical Name	Ac-AEVD-pNA, Caspase-10 Substrate, Colorimetric
Formula	C25H34N6O11
MW	594.7
Appearance	Liquid
Purity	99% by HPLC
Storage Temp	-20°C
Use	Colorimetric substrate for caspases that recognize the amino acid sequence AEVD.

Additional Information

MDL Number	MFCD03787912
ChemACX	X4626951-8
InChI	InChI=1S/C25H34N6O11/c1-12(2)21(30-23(38)17(9-10-19(33)34)28-22(37)13(3)26-14(4)32)25(40)29-18(11-20(35)36)24(39)27-15-5-7-16(8-6-15)31(41)42/h5-8,12-13,17-18,21H,9-11H2,1-4H3,(H,26,32)(H,27,39)(H,28,37)(H,29,40)(H,30,38)(H,33,34)(H,35,36)/t13-,17-,18-,21-/m0/s1
SMILES	C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)Nc1ccc(cc1)[N+](=O)[O-])NC(=O)C
Peptide Sequence	AC-ALA-GLU-VAL-ASP-PNA