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AM-80

品牌：AG Scientific

货号：

规格：10 mg

货期：

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CAS:94497-51-5Formula:C22H25NO3MW:351.444Appearance:Solid

商品详情参考文献相关资料

RARα agonist

Product #	A-2531
CAS #	94497-51-5
Chemical Name	4-[(5,5,8,8-TETRAMETHYL-6,7-DIHYDRONAPHTHALEN-2-YL)CARBAMOYL]BENZOIC ACID
Formula	C₂₂ H₂₅ N O₃
MW	351.444
Appearance	Solid
Solubility	Soluble in 1.1eq. NaOH (100 mM), DMSO (50 mM), methanol, and water
Storage Temp	Room Temp
Therapeutic Area	Oncological Disorders
Use	AM 80 is a retinoic acid receptor α (RARα) agonist that induces differentiation and apoptosis of HL-60 cells displays anticancer activity against acute promyelocytic leukemia

MDL Number	MFCD00866188
ChemACX	X1276933-4
InChI	InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)
SMILES	CC1(CCC(c2c1ccc(c2)NC(=O)c3ccc(cc3)C(=O)O)(C)C)C

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