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A23187, Mixed Calcium-Magnesium Salt
品牌:AG Scientific
货号:
规格:5 mg
货期:

Formula:C56H66CaN4O12.C56H66MgN4O12MW:2038.69Appearance:WhitePowderPurity:>98%(etOAC:Petroleumether8:2)

商品详情 参考文献 相关资料

A23187 has antifungal properties, its antibacterial activities are targeted towards gram positive bacteria. The divalent cation ionophore activity of A23187 is utilized in laborotories to to increase intracellular Ca2+ levels in intact cells.A23187 also induces apoptosis in some cells (e.g. mouse lymphoma cell line, or S49, and Jurkat cells) and prevents it in others (e.g. cells dependent on interlukin 3 that have had the factor withdrawn). Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg (1:1).

 

Additional Information

Product #A-1128
Chemical NameBIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYRROL-2-YL)ETHYL]-5,11-DIOXASPIRO[5.5]UNDECAN-4-YL]METHYL]-1,3-BENZOXAZOLE-4-CARBONYL]OXY]CALCIUM; BIS[[2-[[(3R,4R,6R,7R,9R,10S)-3,7,9-TRIMETHYL-10-[(1S)-1-METHYL-2-OXO-2-(1H-PYR
FormulaC56 H66 Ca N4 O12 . C56 H66 Mg N4 O12
MW2038.69
AppearanceWhite Powder
Purity>98% (etOAC : Petroleum ether 8:2)
SolubilitySoluble in DMSO, Chloroform, and Ethylacetate.
Melting Point309 °C
Storage Temp+4°C
UseA compound used in cell activation

Additional Information

MDL NumberMFCD00213962
ChemACXX6952231-2
InChIInChI=1S/4C28H34N2O6.Ca.Mg/c4*1-15-10-11-28(17(3)13-16(2)26(36-28)18(4)25(31)20-8-6-12-29-20)35-22(15)14-23-30-24-19(27(32)33)7-5-9-21(24)34-23;;/h4*5-9,12,15-18,22,26,29H,10-11,13-14H2,1-4H3,(H,32,33);;/q;;;;2*+2/p-4/t4*15-,16-,17-,18-,22-,26+,28-;;/m1111../s1
SMILESC[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)c3ccc[nH]3)C)C)O[C@@H]1Cc4nc5c(cccc5o4)C(=O)O[Mg]OC(=O)c6cccc7c6nc(o7)C[C@@H]8[C@@H](CC[C@]9(O8)[C@@H](C[C@H]([C@H](O9)[C@H](C)C(=O)c1ccc[nH]1)C)C)C.C[C@@H]1CC[C@@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)
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