Potent inhibitor of mitogen-activated protein kinase kinase-1, Inhibitor of G2 DNA damage checkpoint and cyclin-dependent kinases CDK1/cyclin B and CDK2/cyclin E glycogen synthase kinase-b.

Additional Information

Product #	H-1150
CAS #	82005-12-7
Chemical Name	4-(2-AMINO-4-OXO-2-IMIDAZOLIDIN-5-YLIDENE)-2-BROMO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8-ONE
Formula	C11H10BrN5O2
MW	324.1
Appearance	Yellow needles
Purity	97%
Solubility	Soluble in DMSO (25mg/ml) or Ethanol.
Melting Point	273.54 °C
Storage Temp	-20°C
Therapeutic Area	Neurological Disorders
Use	An ATP competitive, CK1 and GSK-3β inhibitor in Alzheimer’s disease

Additional Information

MDL Number	MFCD04037007
ChemACX	X1461558-2
InChI	InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)/b7-4-
SMILES	c1c2c([nH]c1Br)C(=O)NCC/C2=C/3C(=O)N=C(N3)N