Cyclopamine, Veratrum californicim |产品详情|进口试剂采购网

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Cyclopamine, Veratrum californicim

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CAS:4449-51-8Formula:C27H41NO2MW:411.62Appearance:WhiteCrystallineSolid

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A natural steroidal jerveratrum alkaloide.

Synonyms	11-deoxojervine
Product #	C-1557
CAS #	4449-51-8
Chemical Name	(2'R,3S,3'R,3A'S,6AR,6BS,6'S,7A'R,11AS,11BR)-3',6',10,11B-TETRAMETHYL-1,2,3,3A',4,4',5',6,6A,6B,6',7,7',7A',8,11,11A,11B-OCTADECAHYDRO-3'H-SPIRO[BENZO[A]FLUORENE-9,2'-FURO[3,2-B]PYRIDIN]-3-OL
Formula	C₂₇H₄₁NO₂
MW	411.62
Appearance	White Crystalline Solid
Solubility	Insoluble in Water. Freely soluble in Chloroform, Dichloromethane. Fairly soluble in benzene, warm (50‚ºC-60‚ºC) ethanol (20 mg/mL), DMSO (4 mg/ml) and DMF (10 mg/mL). May recrystalize from ethanolic solution in cold.
Melting Point	225‚ºC-230‚ºC
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A hedgehog [Hh] signaling pathway and Smo inhibitor

MDL Number	MFCD09878269
ChemACX	X1012243-7
InChI	InChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17,19-21,23-25,28-29H,6-14H2,1-4H3/t15-,17+,19-,20-,21-,23-,24+,25-,26-,27-/m0/s1
SMILES	C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1

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