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Cochlioquinone B

品牌：AG Scientific

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规格：0.5 mg

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CAS:32450-26-3Formula:C28H40O6MW:472.6Appearance:YellowLyophilisatePurity:99%(HPLC)

商品详情参考文献相关资料

Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH-ubiquinone reductase inhibitor and a phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A that inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. Cochlioquinones have been recently shown to be antagonists of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1). Newly isolated microbial agent.

Additional Information

Product #	C-1403
CAS #	32450-26-3
Chemical Name	(3R,4AR,6AR,12S,12AS,12BR)-9-[(1S,3S)-1,3-DIMETHYL-2-OXO-PENTYL]-12-HYDROXY-3-(1-HYDROXY-1-METHYL-ETHYL)-6A,12B-DIMETHYL-1,2,3,4A,5,6,12,12A-OCTAHYDROPYRANO[3,2-A]XANTHENE-8,11-DIONE
Formula	C₂₈H₄₀O₆
MW	472.6
Appearance	Yellow Lyophilisate
Purity	99%(HPLC)
Solubility	Soluble in DMSO. Stock solutions store at -20C, good for up to 6 months.
Storage Temp	+4°C
Therapeutic Area	Infectious Diseases
Use	Antiangiogenic and nematocidal activities. Antagonist of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1)

Additional Information

MDL Number	MFCD08062300
ChemACX	X6952242-5
InChI	InChI=1S/C28H40O7/c1-8-14(2)21(30)15(3)16-13-17(29)20-23(32)25-27(6)11-9-18(26(4,5)33)34-19(27)10-12-28(25,7)35-24(20)22(16)31/h13-15,18-19,23,25,32-33H,8-12H2,1-7H3/t14-,15-,18+,19+,23+,25+,27-,28+/m0/s1
SMILES	CC[C@H](C)C(=O)[C@@H](C)C1=CC(=O)C2=C(C1=O)O[C@@]3(CC[C@@H]4[C@@]([C@H]3[C@@H]2O)(CC[C@@H](O4)C(C)(C)O)C)C

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