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上海拜力生物科技公司
Tel:400-968-7988    021-33779008
SU6668
品牌:AG Scientific
货号:
规格:5 mg
货期:

CAS:210644-62-5Formula:C18H18N2O3MW:310.35Appearance:YellowtoDarkyellowSolidPurity:98%

商品详情 参考文献 相关资料
Cell-permeable. A potent and ATP-competitive inhibitor of PDGF, VEGF and FGF receptor tyrosine kinases (RTKs) with ICvalues of 0.06, 2.43, 3.04 and 100M at PDGFR, VEGFR2. FGFR1 and EGFR respectively. Acts as a potent antiangiogenic and antitumor agent.

Additional Information

SynonymsPDGFR Tyrosine Kinase Inhibitor VI
Product #S-2120
CAS #210644-62-5
Chemical Name2,4-DIMETHYL-5-[(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL]-PYRROLE-3-PROPANOIC ACID
FormulaC18H18N2O3
MW310.35
AppearanceYellow to Dark yellow Solid
Purity98%
SolubilityDMSO (~100 mM)
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseA potent ATP-competitive inhibitor against tyrosine kinases.Acts as a potent antiangiogenic and antitumor agent

Additional Information

MDL NumberMFCD09743433
ChemACXX1671181-8
InChIInChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
SMILESCc1c(c([nH]c1/C=C2/c3ccccc3NC2=O)C)CCC(=O)O
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