*Please inquire the availability for this product. Sancycline hydrochloride is the hydrochloride salt of a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.

Additional Information

Synonyms	6-Demethyl-6-deoxytetracycline hydrochloride, NSC 51812
Product #	S-2753
CAS #	6625-20-3
Formula	C21H23ClN2O7
MW	450.9
Appearance	Yellow to orange solid
Purity	>98% by HPLC
Solubility	Soluble in Methanol
Melting Point	224-2280°C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Sancycline Hydrochloride is a semi-synthetic antibiotic

Additional Information

MDL Number	MFCD09842560
InChI	InChI=1S/C21H22N2O7.ClH/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29;/h3-5,9-10,15,24,26-27,30H,6-7H2,1-2H3,(H2,22,29);1H/t9-,10-,15-,21-;/m0./s1
SMILES	CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4cccc(c4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O.Cl