Ready-to-use colorimetric substrate for caspase-4 and related caspases that recognize the amino acid sequence LEVD. Caspase-4 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate LEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for large volume users.

Additional Information

Synonyms	Ac-LEVD-pNA, Caspase-4 Substrate, Colorimetric
Product #	C-2243
Chemical Name	Ac-LEVD-pNA, Caspase-4 Substrate, Colorimetric
Formula	C28H40N6O11
MW	636.65
Appearance	Liquid
Purity	98% by HPLC
Storage Temp	-20°C
Use	Colorimetric substrate for caspase-4 and related caspases that recognize the amino acid sequence LEVD

Additional Information

MDL Number	MFCD01631265
ChemACX	X1206336-4
InChI	InChI=1S/C28H40N6O11/c1-14(2)12-20(29-16(5)35)27(42)31-19(10-11-22(36)37)25(40)33-24(15(3)4)28(43)32-21(13-23(38)39)26(41)30-17-6-8-18(9-7-17)34(44)45/h6-9,14-15,19-21,24H,10-13H2,1-5H3,(H,29,35)(H,30,41)(H,31,42)(H,32,43)(H,33,40)(H,36,37)(H,38,39)
SMILES	CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C
Peptide Sequence	AC-LEU-GLU-VAL-ASP-PNA