Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The antitumor potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A.

Additional Information

Synonyms	Phosphotrienin, CI 920, CL 1565A, PD 110161, NSC 339638
Product #	F-2437
CAS #	87810-56-8
Formula	C19H26NaO9P
MW	452.4
Appearance	White powder
Purity	>95% by HPLC
Solubility	Soluble in water (100 mM), and methanol
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Fostriecin is an antibiotic

Additional Information

MDL Number	MFCD01939908
InChI	InChI=1S/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
SMILES	C[C@](C=C[C@H]1CC=CC(=O)O1)([C@@H](C[C@H](C=CC=CC=CCO)O)O[P](=O)(O)[O-])O.[N a+]