A negative control for the Src family kinase inhibitor PP2 (Cat. No. 1767-1,5). Inhibits the activity of EGFR kinase at an IC.Cooperation between integrin 5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity, Adhesion-dependent Cofilin Serine 3 Phosphorylation by the Integrin-linked Kinase-Src Complex.PKC and cofilin activation affects peripheral actin reorganization and cell-cell contact in cells expressing integrin 5 but not its tailless mutant.

Additional Information

Synonyms	4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine; NSC 1401
Product #	P-2404
CAS #	5334-30-5
Chemical Name	4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine; NSC 1401
Formula	C11H9N5
MW	211.22
Appearance	Beige Solid
Purity	94% by HPLC
Solubility	DMSO (100 mM) and EtOH (25 mM)
Storage Temp	-20°C
Use	PP 3 is a negative control for the Src family protein tyrosine kinase inhibitor PP2

Additional Information

MDL Number	MFCD00022901
ChemACX	X1279595-6
InChI	InChI=1S/C11H9N5/c12-10-9-6-15-16(11(9)14-7-13-10)8-4-2-1-3-5-8/h1-7H,(H2,12,13,14)
SMILES	c1ccc(cc1)n2c3c(cn2)c(ncn3)N