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NVP-AUY922

品牌：AG Scientific

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规格：1 mg

货期：

应用：

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CAS:747412-49-3Formula:C26H31N3O6MW:465.54Appearance:Whitetooff-whiteSolidPurity:99%

商品详情参考文献相关资料

A Hsp90 inhibitor. NVP-AUY922 has excellent potency against Hsp90 in a fluorescence polarization binding assay with an ICof 21 nmol/L against theisoform and of 13 nmol/L for the isoform.

Additional Information

Synonyms	5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Product #	N-2368
CAS #	747412-49-3
Chemical Name	5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Formula	C₂₆H₃₁N₃O₆
MW	465.54
Appearance	White to off-white Solid
Purity	99%
Solubility	DMSO (10 mM)
Melting Point	178-190 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A highly potent HSP90 inhibitor to HSP90α and HSP90β in cancer

Additional Information

MDL Number	MFCD14635361
ChemACX	X1812371-2
InChI	InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)
SMILES	CCNC(=O)c1c(c(on1)c2cc(c(cc2O)O)C(C)C)c3ccc(cc3)CN4CCOCC4

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