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Butyrolactone I
品牌:AG Scientific
货号:
规格:200 ug
货期:

CAS:87414-49-1Formula:C24H24O7MW:424.44Appearance:WhiteSolidPurity:99%byHPLC

商品详情 参考文献 相关资料
Cell permeable. A potent and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. BLI is an important tool for probing the cellular roles of CDKs. It blocks Fas-induced apoptosis and displays antitumor activity.

Additional Information

SynonymsBLI, BL-I
Product #B-2211
CAS #87414-49-1
Chemical NameMETHYL-4-HYDROXY-2-[[4-HYDROXY-3-(3-METHYLBUT-2-ENYL)PHENYL]METHYL]-3-(4-HYDROXYPHENYL)-5-OXOFURAN-2-CARBOXYLATE
FormulaC24H24O7
MW424.44
AppearanceWhite Solid
Purity99% by HPLC
SolubilitySoluble in DMSO (10 mg/ml) and Ethanol (25 mg/ml)
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseAntitumor effects of butyrolactone I, a selective cdc2 kinase inhibitor, on human lung cancer cell

Additional Information

MDL NumberMFCD03453074
ChemACXX1192611-1
InChIInChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-24(23(29)30-3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3
SMILESCC(=CCc1cc(ccc1O)CC2(C(=C(C(=O)O2)O)c3ccc(cc3)O)C(=O)OC)C
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