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BMS-599626

品牌：AG Scientific

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规格：1 mg

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CAS:873837-23-1Formula:C27H27FN8O3.HClMW:567.01Appearance:CrystallineSolidPurity:99%

商品详情参考文献相关资料

An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.

Additional Information

Synonyms	AC480
Product #	B-2207
CAS #	873837-23-1
Chemical Name	(S)-MORPHOLIN-3-YLMETHYL 4-(1-(3-FLUOROBENZYL)-1H-INDAZOL-5-YLAMINO)-5-METHYLPYRROLO[1,2-F][1,2,4] TRIAZIN-6-YLCARBAMATE
Formula	C₂₇H₂₇FN₈O₃.HCl
MW	567.01
Appearance	Crystalline Solid
Purity	99%
Solubility	DMSO
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity

Additional Information

MDL Number	MFCD10565678
ChemACX	X1812385-6
InChI	InChI=1S/C27H27FN8O3/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13-36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20(28)9-18/h2-6,9-11,13,16,22,29H,7-8,12,14-15H2,1H3,(H,34,37)(H,30,32,33)/t22-/m0/s1
SMILES	CC1=C2C(=NC=NN2C=C1NC(=O)OC[C@@H]3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F

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