Selective and strong inhibitor of cyclin-dependent kinases. Inhibits the proliferation of a large range of cells, mainly through arresting the cells in the G2/M phase of the cell cycle.

Additional Information

Product #	I-1076
CAS #	160807-49-8
Chemical Name	3-[1,3-DIHYDRO-3-(HYDROXYIMINO)-2H-INDOL-2-YLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE
Formula	C16H11N3O2
MW	277.3
Appearance	Dark Red Powder
Purity	98%
Solubility	Soluble in DMSO (>25 mg/ml), 100% ethanol (12 mg/ml), and DMF
Melting Point	247-249 °C
Storage Temp	-20°C
Use	Indirubin-3'-monoxime is a potent inhibitor of GSK-3B

Additional Information

MDL Number	MFCD02683594
ChemACX	X1342374-2
InChI	InChI=1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17,21H,(H,18,20)/b15-13-,19-14+
SMILES	C1=CC=C2C(=C1)/C(=C/3C(=NO)C4=CC=CC=C4N3)/C(=O)N2