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Teicoplanin A2-1

品牌：AG Scientific

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规格：1 mg

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应用：

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CAS:91032-34-7Formula:C88H95Cl2N9O33MW:1877.7Appearance:WhitesolidPurity:>98%byHPLC

商品详情参考文献相关资料

Teicoplanin A2-1 is a glycopeptide antibiotic obtained from actinomycetes Actinoplanes teichomyceticus isolated from soil in India. Teicoplanin A2-1 is a mixture of related glycopeptide analogues, with a basic structure characterized with a linear heptapeptide, the distinct carbohydrates D-mannose and D-glycosamine and acyl residue that carries various fatty acids which define the members of the teicoplanin complex. It shows appreciable activity against staphylococci and streptococci, corynebacteria, listeria, and clostridia. It inhibits cell wall biosynthesis in gram-positive organisms by interfering with peptidoglycan polymerization. Teicoplanin A2-1 also fights methicillinresistant Staphylococcus aureus (MRSA).

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Additional Information

Synonyms	Targocid, Ticosin, Antibiotic L 17054
Product #	T-2577
CAS #	91032-34-7
Formula	C₈₈H₉₅Cl₂N₉O₃₃
MW	1877.7
Appearance	White solid
Purity	>98% by HPLC
Solubility	Soluble in DMSO, DMF, ethanol, methanol, and water (poorly)
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	A glycopeptide antibiotic produced by Actinoplanes teichomyceticus

Additional Information

InChI	InChI=1S/C88H95Cl2N9O33/c1-3-4-5-6-7-8-9-10-60(108)94-68-74(113)71(110)58(32-101)129-87(68)132-78-55-26-40-27-56(78)126-52-18-14-38(24-47(52)90)77(131-86-67(92-34(2)103)73(112)70(109)57(31-100)128-86)69-84(121)98-66(85(122)123)45-29-42(105)30-54(127-88-76(115)75(114)72(111)59(33-102)130-88)61(45)44-23-37(13-15-49(44)106)63(81(118)99-69)96-83(120)65(40)97-82(119)64-39-21-41(104)28-43(22-39)124-53-25-36(12-16-50(53)107)62(91)80(117)93-48(79(116)95-64)20-35-11-17-51(125-55)46(89)19-35/h7-8,11-19,21-30,48,57-59,62-77,86-88,100-102,104-107,109-115H,3-6,9-10,20,31-33,91H2,1-2H3,(H,92,103)(H,93,117)(H,94,108)(H,95,116)(H,96,120)(H,97,119)(H,98,121)(H,99,118)(H,122,123)/b8-7-/t48-,57-,58-,59-,62+,63-,64+,65-,66-,67-,68-,69+,70-,71-,72-,73-,74-,75+,76+,77-,86+,87+,88+/m1/s1
SMILES	CCCCC/C=C\CCC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1Oc2c3cc4cc2Oc5ccc(cc5Cl)[C@H]([C@H]6C(=O)N[C@H](c7cc(cc(c7-c8cc(ccc8O)[C@H](C(=O)N6)NC(=O)[C@@H]4NC(=O)[C@@H]9c1cc(cc(c1)Oc1cc(ccc1O)[C@@H](C(=O)N[C@H](Cc1ccc(c(c1)Cl)O3)C(=O)N9)N)O)O[C@@H]1[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)C(=O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)NC(=O)C)CO)O)O

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