*Please inquire the availability for this product. Siccanin is an unusual fused phenolic pentacycle first isolated from Helminthosporium siccans and reported in 1962 as a potent antifungal agent. Siccanin inhibits succinate dehydrogenase in the terminal electron transport system. More recent studies note the proximity of the siccanin to the quinone- of the enzyme. Species-selective inhibition by siccanin is unique among succinate dehydrogenase inhibitors and offers a lead for new chemotherapeutics.

Additional Information

Synonyms	CS 280, SI 23548
Product #	S-2767
CAS #	22733-60-4
Formula	C22H30O3
MW	342.5
Appearance	White solid
Purity	>98% by HPLC
Solubility	Soluble in ethanol, methanol, DMSO, DMF, and water (poorly)
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Siccanin is an potent antifungal agent

Additional Information

MDL Number	MFCD00242750
InChI	InChI=1S/C22H30O3/c1-13-10-14(23)17-15(11-13)25-21(4)9-6-16-20(2,3)7-5-8-22(16)12-24-18(17)19(21)22/h10-11,16,18-19,23H,5-9,12H2,1-4H3/t16?,18?,19-,21?,22?/m0/s1
SMILES	Cc1cc(c2c(c1)OC3(CCC4C(CCCC45[C@H]3C2OC5)(C)C)C)O