*Please inquire the availability for this product. Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogues in the antimycin A class, mostly involving variation of the fatty acid ester chain length or adjacent alkyl starting unit. Antimycin A binds to cytochrome C reductase at the Qi site, inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A is widely used as a bioprobe of respiration and other applications with over 5,000 literature citations.

Additional Information

Synonyms	Antipiriculin, Levoristatin, Virosin, Vulgarin
Product #	A-2625
CAS #	1397-94-0
Formula	C28H40N2O9 (for A1)
MW	548.6 (for A1)
Appearance	White solid
Purity	>95% by HPLC
Solubility	Soluble in 100% ethanol (50 mg/ml) Insoluble in water
Melting Point	162-164 °C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	An antibiotic that induces apoptosis

Additional Information

MDL Number	MFCD01779723
InChI	InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20?,23+,25+/m1/s1
SMILES	CCCCCCC1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)c2cccc(c2O)NC=O)C)OC(=O)CC(C)C