*Please inquire the availability for this product. Methacycline is a semi-synthetic tetracycline prepared by dehydration of the 6-hydroxy group of oxytetracycline to yield an exocyclic 6-methylene. Like all tetracyclines, methacycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Methacycline has been extensively cited in the literature with over 400 references.

Additional Information

Synonyms	6-Methyleneoxytetracycline, Metacycline, Rondomycin
Product #	M-2565
CAS #	914-00-1
Formula	C22H22N2O8
MW	442.4
Appearance	Yellow to orange solid
Purity	>98% by HPLC
Melting Point	313.72 °C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	A tetracycline with broad range antibacterial and antiprotozoal properties

Additional Information

MDL Number	MFCD00800598
InChI	InChI=1S/C22H22N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31)/t10-,14-,15+,17+,22+/m1/s1
SMILES	CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C(=CC=C4)O)C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O