*Please inquire the availability for this product. Galiellalactone was originally isolated from Galiella rufa as a plant growth regulator. Recently it was shown to inhibit IL-6 induced SEAP expression with IC50 values of 250-500 nM, blocking the binding of the activated Stat3 dimers to their DNA s without inhibiting the tyrosine and serine phosphorylation of the Stat3 transcription factor.

Additional Information

Product #	G-2503
CAS #	133613-71-5
Formula	C11H14O3
MW	194.2
Appearance	White Lyophilisate
Purity	>95% by HPLC
Solubility	Soluble in 100% ethanol, methanol, DMF, and DMSO
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Galiellalactone is a Direct Inhibitor of STAT3 in Prostate Cancer Cell

Additional Information

MDL Number	MFCD11111607
InChI	InChI=1S/C11H14O3/c1-6-4-7-2-3-9-11(7,13)8(5-6)10(12)14-9/h5-7,9,13H,2-4H2,1H3/t6-,7+,9+,11-/m0/s1
SMILES	O=C/1O[C@@H]3CC[C@@H]2C[C@@H](/C=C\1[C@@]23O)C