Natural omega-3 fatty ester. EPA competitively inhibits the metabolism of (ω-6) arachidonic acid by cyclooxygenase enzymes,2 suggesting that EPA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism. In addition, dietary EPA ethyl ester in rats increases fatty acid β-oxidation enzyme levels,3,4 indicating that EPA ethyl ester may alter the expression of genes related to fatty acid metabolism.
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