Quinupristin-Dalfopristin mesylate complex |产品详情|进口试剂采购网

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Quinupristin-Dalfopristin mesylate complex

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Quinupristin-Dalfopristin mesylate complex

品牌：AG Scientific

货号：

规格：5 mg

货期：

应用：

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CAS:126602-89-9Formula:C87H117N13O19S2MW:1713.06558Appearance:WhitetolightyellowsolidPurity:>98%byHPLC

商品详情参考文献相关资料

*Please inquire the availability for this product. Quinupristin-dalfopristin mesylate complex is a 70:30 (w/w) complex of two semi-synthetic analogues marketed as Synercid. Dalfopristin is a semisynthetic analogue of virginiamycin M, while quinupristin is a semi-synthetic analogue of virginiamycin B. To optimise stability, the compounds are presented as the mesylate salts with 10% sodium mesylate excess to provide a buffered aqueous solution. The complex is more hydrophobic than the naturally-occurring virginiamycin complex, with a readily ionisable group for generating a salt for improved solubility. There is little published data on the synthesis and biological activity of individual components of the complex, however the combination is a highly effective antibiotic, including activity against resistant strains.

Additional Information

Synonyms	Synercid complex, Dalfopristin-Quinupristin complex
Product #	Q-2431
CAS #	126602-89-9
Formula	C₈₇H₁₁₇N₁₃O₁₉S₂
MW	1713.06558
Appearance	White to light yellow solid
Purity	>98% by HPLC
Solubility	Soluble in ethanol, methanol, DMSO, and DMF
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	The combination is a highly effective antibiotic, including activity against resistant strains

Additional Information

MDL Number	MFCD07364059
InChI	InChI=1S/C53H67N9O10S.C34H50N4O9S/c1-6-37-50(68)61-23-11-14-38(61)51(69)59(5)40(26-32-16-18-36(19-17-32)58(3)4)52(70)62-28-35(30-73-43-29-60-24-20-33(43)21-25-60)42(64)27-39(62)47(65)57-45(34-12-8-7-9-13-34)53(71)72-31(2)44(48(66)55-37)56-49(67)46-41(63)15-10-22-54-46;1-7-37(8-2)16-17-48(44,45)28-13-15-38-31(28)34(43)47-32(22(3)4)24(6)11-12-29(41)35-14-9-10-23(5)18-25(39)19-26(40)20-30-36-27(21-46-30)33(38)42/h7-10,12-13,15-19,22,31,33,35,37-40,43-45,63H,6,11,14,20-21,23-30H2,1-5H3,(H,55,66)(H,56,67)(H,57,65);9-12,18,21-22,24-25,28,31-32,39H,7-8,13-17,19-20H2,1-6H3,(H,35,41)/b;10-9-,12-11-,23-18-/t31-,35+,37-,38+,39?,40+,43-,44+,45+;24-,25-,28-,31-,32-/m11/s1
SMILES	CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3C[C@H](C(=O)CC3C(=O)N[C@H](C(=O )O[C@@H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CS[C@@H]6CN7CCC6C C7)CC8=CC=C(C=C8)N(C)C)C.CCN(CC)CCS(=O)(=O)[C@@H]1CCN2[C@H]1C(=O)O[C@@H]([C@ @H](/C=CC(=O)NC/C=CC(=C/[C@H](CC(=O)CC3=NC(=CO3)C2=O)O)C)C)C(C)C

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